Efecto inhibitorio in vitro del extracto etanólico de las hojas de Aloysia citrodora L (CEDRON) sobre el crecimiento de Staphylococcus aureus y Escherichia coli
Fecha
2025
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Universidad Nacional San Luis Gonzaga.
Resumen
La resistencia antimicrobiana es un problema que amenaza la salud mundial. En este sentido se
ha sugerido la búsqueda de nuevos compuestos con actividad antimicrobiana por lo que se
planteó determinar el efecto inhibitorio el extracto etanólico de las hojas de Aloysia citrodora L
(cedrón) sobre el crecimiento de Staphylococcus aureus y Escherichia coli. Se recolectaron las
hojas a estudiar procedentes de Huancayo para su desecación y posterior molienda. El extracto
etanólico se obtuvo mediante la técnica de maceración por 48 horas y se evaluó a diferentes
concentraciones aplicándose el método de difusión en disco (Método de Kirby Bauer) por
triplicado, obteniéndose que el extracto etanólico de las hojas de Aloysia citrodora L
(CEDRON) a diferentes concentraciones mostró mayor efecto inhibitorio sobre la cepa de
Staphylococcus aureus mientras que la cepa de Escherichia coli presentó resistencia bacteriana.
El porcentaje de inhibición relativa sobre las cepas de Staphylococcus aureus y Escherichia coli,
fué de 85.7 % y 36.7 % respectivamente. Se concluye que las hojas de Aloysia citrodora L
presentan buena actividad antimicrobiana, por tanto pueden aportar compuestos biológicamente
activos contra enfermedades infecciosas.
Antimicrobial resistance is a problem that threatens world health. In this sense, the search for new compounds with antimicrobial activity has been suggested, so it was proposed to determine the inhibitory effect the ethanolic extract of citrodora l (cedron) aloysia leaves on the growth of Staphylococcus aureus and Escherichia coli. The leaves to be studied from Huancayo for desiccation and subsequent grinding were collected. The ethanolic extract was obtained by the maceration technique for 48 hours and was evaluated to different concentrations by applying the disk dissemination method (Kirby Bauer method) in triplicate, obtaining that the ethanolic extract of the citrodora l leaves Citrodora L (CEDRON) At different concentrations it showed a greater inhibitory effect on Staphylococcus aureus strain while Escherichia coli strain presented bacterial resistance. The percentage of relative inhibition on the strains of Staphylococcus aureus and Escherichia coli, was 85.7 % and 36.7 % respectively. It is concluded that citrodora L leaves have good antimicrobial activity, therefore they can provide biologically active compounds against infectious diseases.
Antimicrobial resistance is a problem that threatens world health. In this sense, the search for new compounds with antimicrobial activity has been suggested, so it was proposed to determine the inhibitory effect the ethanolic extract of citrodora l (cedron) aloysia leaves on the growth of Staphylococcus aureus and Escherichia coli. The leaves to be studied from Huancayo for desiccation and subsequent grinding were collected. The ethanolic extract was obtained by the maceration technique for 48 hours and was evaluated to different concentrations by applying the disk dissemination method (Kirby Bauer method) in triplicate, obtaining that the ethanolic extract of the citrodora l leaves Citrodora L (CEDRON) At different concentrations it showed a greater inhibitory effect on Staphylococcus aureus strain while Escherichia coli strain presented bacterial resistance. The percentage of relative inhibition on the strains of Staphylococcus aureus and Escherichia coli, was 85.7 % and 36.7 % respectively. It is concluded that citrodora L leaves have good antimicrobial activity, therefore they can provide biologically active compounds against infectious diseases.
Descripción
Palabras clave
Efecto inhibitorio, Extractos vegetales, Cepas bacterianas, Inhibitory effect
